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Until Proven Safe

The History and Future of Quarantine

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Geoff Manaugh and Nicola Twilley have been researching quarantine since long before the COVID-19 pandemic. With Until Proven Safe, they bring us a book as compelling as it is definitive, not only urgent reading for social-distanced times but also an up-to-the-minute investigation of the interplay of forces–––biological, political, technological––that shape our modern world.
Quarantine is our most powerful response to uncertainty: it means waiting to see if something hidden inside us will be revealed. It is also one of our most dangerous, operating through an assumption of guilt. In quarantine, we are considered infectious until proven safe.
Until Proven Safe tracks the history and future of quarantine around the globe, chasing the story of emergency isolation through time and space—from the crumbling lazarettos of the Mediterranean, built to contain the Black Death, to an experimental Ebola unit in London, and from the hallways of the CDC to closed-door simulations where pharmaceutical execs and epidemiologists prepare for the outbreak of a novel coronavirus.
But the story of quarantine ranges far beyond the history of medical isolation. In Until Proven Safe, the authors tour a nuclear-waste isolation facility beneath the New Mexican desert, see plants stricken with a disease that threatens the world's wheat supply, and meet NASA's Planetary Protection Officer, tasked with saving Earth from extraterrestrial infections. They also introduce us to the corporate tech giants hoping to revolutionize quarantine through surveillance and algorithmic prediction.
We live in a disorienting historical moment that can feel both unprecedented and inevitable; Until Proven Safe helps us make sense of our new reality through a thrillingly reported, thought-provoking exploration of the meaning of freedom, governance, and mutual responsibility.

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    • Library Journal

      December 1, 2020

      Quarantine: it's come to stay, but where did it come from as an idea? BLDGBLOG founder Manaugh and Twilley, cohost of the award-winning podcast Gastropod, track its history from the lazarettos and quarantine islands of Venice--built before anyone knew what a communicable disease really was--to the scientists now envisioning ways to make future quarantines more effective. With a 50,000-copy first printing.

      Copyright 2020 Library Journal, LLC Used with permission.

    • Publisher's Weekly

      Starred review from May 10, 2021
      BLDGBLOG blogger Manaugh (A Burglar’s Guide to the City) and Gastropod host Twilley take a riveting and timely look at how humanity has protected itself by isolating segments of its populations. Quarantines, they write, have “always been a stimulus for creatively rethinking the built environment,” and while the authors cover the response to Covid-19, they also survey the ways animals avoid infecting others, agricultural safeguards against diseases that could decimate food supplies, precautions taken by NASA to not contaminate other planets, and how radioactive nuclear waste can be safely stored for tens of thousands of years. Manaugh and Twilley cull their research into a concise and logical series of recommendations for future public health crises, grounded in a deep appreciation of the human impact of quarantining. Though technological advances in tracking, testing, and containment offer promise for more effective quarantining, the future will likely see more quarantines, and thus will require “a politics and culture of collaboration.” The way forward, they write, will require design creativity, legal reforms that ensure “that the authorities making... promises will deliver on them,” and imaginatively thinking about quarantine as an experience that allows agency. This thoughtful study couldn’t arrive at a better moment. Agent: Nathaniel Jacks, InkWell Management.

    • Booklist

      June 1, 2021
      Quarantine. ""The very word--foreign, clinical, medieval--inspired fear,"" write Manaugh and Twilley in their engrossing examination of protective isolation. Surveying six centuries of society's often initial response to epidemics, they deem quarantine a ""powerful and dangerous tool."" An island near Dubrovnik, NASA, Nebraska, and Venice are a few destinations on the authors' itinerary. The Black Death, cholera, and COVID-19 are some of the infections considered. Quarantine provides a buffer and a delay, offering space and time, between the known (healthy folks) and the dangerous (potentially contagious people). Its complicated nature is adeptly explored, including ethical concerns, legal and moral questions, and enforcement challenges. Risks, uncertainty, security, and architectural design associated with preemptive seclusion are discussed. Descriptions of the many ways mail has been disinfected (grilling, smoking, application of vinegar, processing through weird gadgets) in prior epidemics and lessons on infection-control behavior gleaned from social insects make for fascinating reading. ""Quarantine, a solution from the past, is back--and here to stay,"" the authors warn. In the future, its role will be shaped increasingly by technology and the attitude of citizens.

      COPYRIGHT(2021) Booklist, ALL RIGHTS RESERVED.

    • Library Journal

      July 1, 2021

      Authors Twilley (co-host of the podcast Gastropod) and Manaugh (A Burglar's Guide to the City) began their research on the practice of quarantine long before the start of the global COVID-19 pandemic, yet they always knew their book would be more than just a history of quarantine. They point out other instances of the practice, including in modern agriculture that depends on quarantine as a means of protection, especially as humans become more dependent on monoculture farming. Space exploration requires quarantine too, so that humans do not destroy other planetary ecosystems by transmitting Earth-based contagions. The global spread of COVID-19 and the subsequent viral flare-ups demonstrate a continuing need for separation and isolation; quarantine is still an effective tool in protecting public health, the authors say. Twilley and Manaugh argue, however, that quarantine's effectiveness must be balanced against historical knowledge and the conditions we see today around diseases like Ebola; they prove that quarantine, when used as a way to protect one's self, family, or society, can also allow the flourishing of racism, xenophobia, and oppression of targeted populations, including the revocation of personal freedoms. This book looks forward to new technologies and legal changes that may alter the way we travel and interact within our own homes to stay safe. VERDICT An informative account for readers interested in public health's impact on historical and current practices in medicine and science.--Rachel M. Minkin, Michigan State Univ. Libs., East Lansing

      Copyright 2021 Library Journal, LLC Used with permission.

    • Kirkus

      Starred review from May 15, 2021
      A captivating survey of the uses and abuses of quarantines, from the days of the Black Death to the lockdowns of Covid-19. Journalists Manaugh and Twilley meld a global view of a timely subject with vividly detailed accounts of quarantines, whether of people or hazardous plants, animals, and chemicals such as nuclear waste. The authors show how--since the emergence of "lazarettos," the quarantine hospitals of medieval Venice and other Adriatic ports--authorities have strived to contain dreaded hazards. Among many others, these have included the bubonic plague, yellow fever, tuberculosis, Ebola, and cholera. Yet some problems resist solutions. "Although the advent of advanced contagion modeling, location tracking, and data mining offer the promise of refining quarantine, rendering it so minimal and precise as to be almost imperceptible," the authors write, "the use of those tools during COVID-19 has demonstrated that, in many ways, effective quarantine has changed remarkably little since its origins during the Black Death." Persistent challenges include the tedium of isolation, the architectural rigors of designing suitable facilities, and the xenophobic use of quarantine "to obstruct the passage of undesirable immigrants at the border and stigmatize those who have already arrived." For such risks, the authors propose fresh, sensible remedies such as a "bill of rights" for the quarantined. But a larger charm of this smart book lies in their ability to bring potentially dry topics to life. They profile the delightfully "obsessive" founder of the Disinfected Mail Study Circle (which tracks epidemics through postal evidence), and, after visiting a greenhouse near London, they note that cacao-plant diseases have contributed to a shrinking global chocolate supply that may lead to a "chocpocalypse." Chocoholics, beware: One study found that in a decade or so, "a Hershey bar may well be as rare and expensive as caviar." An infectiously appealing overview of efforts to contain the potentially infectious.

      COPYRIGHT(2021) Kirkus Reviews, ALL RIGHTS RESERVED.

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